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Organ-specific effects of cystic fibrosis
©1997, Jeffrey J. Wine, Ph.D.
· Cystic fibrosis is primarily an exocrinopathy
Cystic fibrosis is manifestly a disease of exocrine organs, if we recall that the respiratory, digestive and reproductive tracts all rely extensively on exocrine secretions. In cystic fibrosis, the lungs lose their ability to maintain a sterile surface and are gradually destroyed by colonies of bacteria. The intestinal lining secretes less fluid than normal, and is ...
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